Sample Management Manager

POSITION SUMMARY:

Join Natera’s R D operations as the Sample Management Manager . You will direct biobanking, cold chain logistics, and the full lifecycle of clinical diagnostic samples. Every sample represents a real person, and you will ensure that tracking, storage, and distribution meet the rigorous standards required to advance cell-free DNA testing. You will lead a high-performing team, optimizing workflows and using data to maintain accuracy and regulatory adherence in a high-stakes clinical environment.

PRIMARY RESPONSIBILITIES:

Develop and implement standardized procedures for sample intake, storage, tracking, and distribution

Treat regulatory guidelines (e.g., GMP, GLP, ISO) and company policies as the foundation of your work, ensuring strict compliance

Manage Laboratory Information Management Systems (LIMS) to maintain sample integrity and traceability

Lead, train, and develop the Sample Management team to operate with pace and precision

Think team by partnering directly with R D, Quality, Supply Chain, and external partners to align sample management practices without needing translation layers

Use data to troubleshoot discrepancies, root-cause logistical issues, and resolve quality concerns

Use data to pressure-test workflows and implement technology enhancements that improve precision and scale

Prepare rigorous reports and audits to support quality assurance and regulatory inspections

Operational Responsibilities

Take ownership of sample management operations, proactively allocating resources and designing workflows to meet rigorous clinical timelines

Provide clear guidance to the team, establishing policies and removing operational bottlenecks without relying on heavy hierarchy

Take ownership of operational challenges, relying on data rather than opinion to resolve workflow and capability gaps

Manage scheduling, performance requirements, and operational budgets

Act as an advisor to the team, directly stepping in to assist with issue resolution and technical troubleshooting

Team Performance Management

Direct team members to ensure precise execution of SOPs and safety procedures

Oversee training for new hires and build an execution-focused culture

Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and discuss goals

Plan and lead shift meetings, fostering team alignment and professionalism

Approve timecards, PTO requests, and ensure consistent staffing coverage

Prioritize workloads dynamically, delegate responsibilities, and escalate issues without hesitation

Compliance Quality Assurance

Treat quality as part of performance by ensuring all regulatory agency requirements are met through proper documentation, audits, and corrective actions

Maintain strict compliance with HIPAA/PHI privacy policies and complete required training within 30 days of hire

Oversee sample processing, ensuring accurate documentation and adherence to departmental expectations

Support R D leadership in initiating and executing new projects to enhance operational efficiency

QUALIFICATIONS:

BS/BA degree (Master’s degree preferred) in Medical Technology, Biological Sciences, or a related field

8+ years of related experience with a bachelor’s degree

Minimum 3 years of team management experience

KNOWLEDGE, SKILLS, AND ABILITIES:

Demonstrated team management experience in a fast-paced, regulated environment

Ability to manage projects independently with an ownership mindset

Clear, direct communication and troubleshooting skills

Excellent pipetting, data analysis, and wet lab operations abilities

Proficiency in Laboratory Information Management Systems (LIMS) and data analysis tools

Experience with Molecular Biology, Good Manufacturing Practice (GMP), and Quality System Regulation (QSR)

Strong Excel and data management software experience

Ability to analyze and improve operational processes for efficiency and compliance using data

Experience with biorepository sample management is a plus

Strong knowledge of regulatory requirements in sample handling is preferred

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Austin, TX

$99,500 $124,400 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our …