Research Associate 2

POSITION SUMMARY:

Join Natera’s R D Scientific Operations as a Research Associate 2 on the Sample Processing team. You will execute Next-Generation Sequencing (NGS) workflows, cell-free DNA (cfDNA) extraction, and library preparation, generating the high-quality data required to advance our clinical diagnostic assays. Every sample represents a real person, and you will ensure accuracy, ethics, and compliance in sample management to directly impact patient care.

PRIMARY RESPONSIBILITIES:

Isolate plasma and buffy coat from whole blood and normalize plasma samples

Extract nucleic acids from whole blood or plasma using automated and manual extraction methods

Perform library preparation for Next-Generation Sequencing (NGS) using automated and manual methods

Determine the quantity and quality of nucleic acids using Quant-IT, Qubit, Nanodrop, BioAnalyzer, and qPCR

Load libraries onto NGS platforms, including NextSeq, MiSeq i100, NovaSeq, NovaSeq X Plus, and Revio

Interpret data to determine appropriate next steps based on rigorous outlined requirements

Perform routine laboratory equipment maintenance as defined in Standard Operating Procedures (SOPs)

Troubleshoot minor equipment malfunctions using data, escalating to the R D equipment support team when necessary

Track sample inventory and status using Laboratory Information Management Systems (LIMS) and Google Sheets

Maintain precise records of lab work in LIMS, Google Sheets, Excel, and internal databases

Periodically review or draft SOPs and other work instructions

Take ownership of process improvements to increase operational precision and scale

Think team by partnering directly with R D staff to define process needs and execute lab work without needing translation layers

Ensure accurate, ethical, and appropriate management of samples in compliance with all applicable federal regulations

Adapt to evolving science and operational needs, executing tasks that move the work forward

Handle protected health information (PHI) in paper and electronic formats as required to perform duties

Complete required HIPAA/PHI privacy and security training within the first 30 days of hire and maintain current status on all training

QUALIFICATIONS:

BS/BA in a biological science or equivalent

Minimum of 2 years of related laboratory experience

Must pass a post-offer criminal background check

KNOWLEDGE, SKILLS, AND ABILITIES:

Extensive familiarity with good pipetting practices using single and multi-channel micropipettes and serological pipettes

Direct hands-on experience with library preparation and NGS platforms

Experience with laboratory automation systems (e.g., Tecan, Hamilton, Beckman-Coulter) is strongly preferred

Able to operate independently in the lab with strict attention to detail and precision

Proficiency with Laboratory Information Management Systems (LIMS) and database software

Proficiency with Microsoft Office (Word, Excel) and Google Drive

Clear, direct oral and written communication skills

Ability to think analytically, testing assumptions with data to troubleshoot and solve problems

Demonstrated strong interpersonal skills to build effective working relationships within the functional area

Manage competing priorities while operating with pace and precision in an evolving scientific environment

PHYSICAL DEMANDS AND WORK ENVIRONMENT:

Duties are typically performed in an office and laboratory setting daily

Requires the ability to perform repetitive motions during pipetting and sample processing

Requires the ability to use a computer keyboard, communicate over the telephone, and read printed material

May require lifting or moving items weighing up to 25lbs

Compensation Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and skills considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

Comprehensive health benefits (medical, dental, vision)

401(k) with company match

Generous paid time off and company holidays

Additional wellness and work-life benefits

Compensation Range

$74,800 $93,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challen…