Director, Investor Relations

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

Join Amylyx at a pivotal moment of growth and visibility as our Director, Investor Relations —a high-impact role at the center of our corporate story, strategy, and market presence. In this position, you’ll work side-by-side with the VP of Investor Relations Communications and partner closely with our senior leadership team—including our co-CEOs, CFO, CMO, and CCO—to shape how the investment community understands and values our mission.

You’ll serve as a strategic advisor and storyteller, helping to translate complex science and financial performance into a clear, compelling narrative that resonates with investors and analysts. You’ll play a key role in strengthening our investor engagement program, building meaningful relationships, and influencing how Amylyx is perceived in a dynamic and evolving healthcare landscape.

Responsibilities

Support the development and execution of investor relations plans and initiatives aligned with corporate goals during a period of dynamic growth, while helping to define and drive a forward-looking 12–24 month IR strategy in partnership with senior leadership and the Board, ensuring alignment with long-term corporate objectives

Engage with the investment community, including healthcare investors and equity research analysts, represent Amylyx at events, and, over time, become a primary relationship owner for select sell-side analysts and new buy-side accounts

Write quarterly and annual results communications, including financial results press releases, annual reports, conference call scripts, key messages, Q As, and other documents to communicate to investor and analyst audiences

Partner with colleagues to prepare documents for filings and disclosures to be compliant with SEC regulations (i.e., 8-Ks, 10-Ks, 10-Qs, proxies); in certain circumstances, lead creation of documents for filings

Write and create investor-facing materials, including press releases, presentations for investor meetings, key message documents, Q As, and content for website; lead and make update as appropriate

Partner with leadership and other colleagues to ensure consistency of messaging

Participate in one-on-one meetings, bus tours, conferences, and non-deal roadshows, and lead follow-up when appropriate

Respond to requests for information from external stakeholders, including shareholders, in a timely manner

Review and analyze analyst research and models, consensus estimates, and market-related trends impacting valuation and perception; summarize market sentiment on Amylyx and continue to manage consensus

Analyze peer companies’ communications, peer sell-side research, industry and communication trends and compile reports for leadership that support investor interactions

Partner with Senior IR and Communications Operations Specialist who manages active IR calendar/schedules and prepares background information on investors in advance of meetings; assist with scheduling, preparations, and investor tracking when needed

Support the overall Investor Relations function, including assisting with day-to-day needs and long-term special projects

Required Qualifications

Bachelor’s degree required

10+ years of experience, including 5+ years of experience on commercial biotech or pharma team

Background in Investor Relations, Corporate Finance, Equity Research, Buy-Side, or Consulting preferred

Strong understanding of financial modeling and how analysts assess company performance and valuation

Knowledge of SEC regulations, disclosure requirements, and management of material non-public information

Executive presence with the ability to influence and counsel senior leaders

Exceptional written, verbal, and presentation skills across diverse internal and external audiences

Ability to translate complex scientific, clinical, and financial information into clear, compelling messaging

Strong understanding of investor priorities and market expectations

Sound judgment and composure in high-pressure environments

Work Location and Conditions

At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to h…