Sr. Project Manager

COMPANY DESCRIPTION:

A career here is life-enhancing.

At Syner-G, we enable our people to build careers that impact positively on their quality of life. Through our expertise, insight, consulting and management skills, we accelerate breakthrough science and delivery of life-enhancing therapies to more patients. We work across a diverse range of clients and projects, supporting many organizations from the most critical phases of the drug discovery and approval process through to commercialization. It is meaningful, varied and thought-provoking work with a strategic emphasis, a solutions-driven approach and significant, real-world outcomes, from science to delivery/success. To learn more about who we are and what drives us, watch our company video here .

Underpinning this mission is a culture that aligns perfectly with what we want to achieve. We enable our people to grow, we support them in their learning and we reward them in so many different ways. In return, they play an instrumental role in maintaining our reputation across the globe as a strategic biopharma product development and delivery partner.

Syner-G was recently honored with BioSpace's prestigious "Best Places to Work" 2026 award, for the third consecutive year, along with many other award-winning programs to make a career here truly life-enhancing. These recognitions are a testament to our commitment to fostering a positive and engaging work environment for our employees, with a particular emphasis on culture, career growth and development opportunities, financial rewards, leadership and innovation.

At Syner-G, we recognize that our team members are our most valuable asset. Join us in shaping the future, where your talents are valued, and your contributions make a meaningful impact.

For more information, visit www.Synergbiopharma.com

POSITION OVERVIEW:

We are seeking a Sr. Manager with 10-15 years of experience to lead and oversee complex Commissioning, Qualification, Validation (CQV), HVAC, facility, utility, and operational readiness initiatives within GMP-regulated life sciences environments. The ideal candidate will have extensive experience managing cross-functional teams, driving commissioning and qualification programs for pharmaceutical manufacturing facilities, cleanrooms, utilities, and support systems, and ensuring alignment with organizational goals, regulatory expectations, and client requirements. This role requires strong leadership, deep technical expertise in HVAC systems, cleanroom environments, facility utilities, and risk-based CQV methodologies, as well as the ability to manage multiple high-visibility workstreams from planning through execution, turnover, and operational readiness. The successful candidate will serve as a key leader in coordinating construction, engineering, automation, validation, quality, and operations teams to deliver compliant and efficient project execution.

WORK LOCATION:

Travel to client sites may be required up to 100%, depending on project needs and client expectations.

KEY RESPONSIBILITIES:

(This list is not exhaustive and may be supplemented or adjusted as needed.)

Provide strategic leadership and oversight for projects spanning HVAC systems, facility infrastructure, commissioning, qualification, validation, startup, and operational readiness.

Lead overall C Q execution strategy for assigned manufacturing areas, utilities, cleanrooms, HVAC systems, and support systems within GMP-regulated facilities.

Manage commissioning, qualification, validation, startup, and turnover activities from construction completion through operational readiness and handoff to operations.

Lead HVAC project execution activities across pharmaceutical manufacturing, laboratory, utility, and support areas.

Coordinate daily activities of CQV engineers, contractors, vendors, and third-party service providers to ensure successful project execution.

Develop and maintain integrated C Q schedules aligned with construction, automation, startup, and manufacturing readiness milestones.

Develop and manage project plans, schedules, budgets, resource strategies, and risk mitigation activities across multiple workstreams.

Coordinate HVAC, facility, utility, and CQV scope with construction, automation, facilities, manufacturing, quality, and engineering teams.

Facilitate and lead system impact assessments, criticality assessments, boundary reviews, and turnover planning activities.

Oversee cleanroom implementation including airflow design, pressurization cascades, environmental controls, and contamination control strategies to meet GMP requirements.

Manage contractors, vendors, schedules, field execution activities, startup efforts, and punch list resolution through project completion.

Drive HVAC startup, commissioning, qualification (IQ/OQ/PQ), validation, and operational readiness activities in alignment with project CQV strategies.

Support Factory Acceptance Tests (FATs), Site Acceptance Tests (SATs), vendor…