Manager, HR Operations
Jadebiosciences · Boston; Remote; San Francisco; Seattle · Posted Jul 3, 2026
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About Jade Biosciences
Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn .
Role Overview
As a growing startup company, Jade is looking for a hands-on Manager, HR Operations to build scalable processes and partner with our teams to enable Jade’s great culture. The Manager, HR Operations will lead and optimize HR processes, systems, benefits administration, and employee lifecycle operations. This individual will lead the efficient delivery of HR services while ensuring streamlined and compliant processes and amazing employee experiences. The Manager, HR Operations will partner closely with Payroll, Finance, IT, and business leaders to support Jade’s teams and growth.
Key Responsibilities
Benefits Administration
Oversee administration of health and welfare benefits, retirement plans and leave programs
Manage new hire, annual open enrollment and employee benefit communications
Partner with brokers and vendors to ensure effective program administration
Monitor benefits compliance, audits, and reporting requirements
Support benefits strategy by analyzing utilization, trends, and costs
Payroll Employee Lifecycle Support
Collaborate with Payroll to ensure accurate employee data and timely processing
Oversee onboarding, offboarding, employee status changes, and record management
Manage HR documentation and personnel file administration
Ensure seamless end-to-end employee experiences
HR Operations
Lead the day-to-day administration and execution of HR operations
Develop, implement, and streamline HR processes, policies, and procedures
Manage HR operational projects and initiatives from planning through implementation
Ensure compliance with federal, state, and provincial employment laws and regulations in the US and Canada
Maintain HR policies, procedures, and employee records in accordance with legal requirements
Stay informed of employment law changes and recommend process updates as needed
Partner with Legal and Finance on compliance-related initiatives
HR Systems and Data Management
Lead the administration of HR systems and ensure the accuracy, integrity, and security of employee data
Manage system configurations, workflows, security roles, reporting, and integrations
Lead HR systems enhancements and implementation projects
Develop dashboards and reports to support decision making
Partner with Payroll and IT to ensure seamless system functionality
Qualifications
Bachelor’s degree and 5-8 years of HR experience with 3+ years of progressive benefits, HR systems, and compliance experience required
Experience in startup, high-growth organizations required, biotechnology experience preferred
Experience administering benefits, HR systems and HR processes in a fast paced, growing organization
Experience supporting US multi-state employee populations required, experience supporting Canadian employees preferred
Strong knowledge of HR operations, benefits administration, and employment law
Advanced HR systems and technology expertise including experience with HRIS platforms such as Paylocity
Strong analytical and project management skills
Strong attention to detail and commitment to data accuracy
Ability to manage multiple priorities, competing deadlines and meet those deadlines
Strong communication skills
This is a remote role; periodic travel to team and company events is required.
The anticipated salary range for candidates for this role is $135,000 - $155,000 . The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.
As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster .
Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.